I1774

Iturin A from Bacillus subtilis

≥95% (HPLC), suitable for microbiological culture

• CAS Number: 52229-90-0
• UNSPSC Code: 12352202
• NACRES: NA.61
• MDL number: MFCD01094135

Properties

• Product Name: Iturin A from Bacillus subtilis, ≥95% (HPLC)
• biological source: Bacillus subtilis
• Quality Segment: 200
• assay: ≥95% (HPLC)
• form: powder
• technique(s): microbiological culture: suitable
• color: white to yellow
• solubility: ethanol: soluble 9.80-10.20 mg/mL
• antibiotic activity spectrum: fungi
• mode of action: cell membrane | interferes
• storage temp.: 2-8°C

Description

Application

Iturin A was used in the study of Bacillomycin D (an iturin with antifungal activity against Aspergillus flavus).

Biochem/physiol Actions

IturinA exhibits strong antifungal activity against pathogenic yeast and fungi. It interacts with the cytoplasmic membrane of the target cell forming ion conducting pores. Its mode of action could be attributed to its interaction with sterols and phospholipids. The compound causes the release of exo-vesicles from human erythrocytes.

Other Notes

A family of lipopeptides characterized by a heptapeptide cyclized with a C₁₃-C₁₇ β-amino fatty acid. Composed mainly of C₁₄-C₁₅ β-amino acids.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)