F8791

5-Fluoro-5′-deoxyuridine

• Synonym(s): Doxifluridine, 5′dFUrd
• Empirical Formula (Hill Notation): C₉H₁₁FN₂O₅
• CAS Number: 3094-09-5
• Molecular Weight: 246.19
• NACRES: NA.77
• PubChem Substance ID: 24278444
• UNSPSC Code: 12352200
• EC Number: 221-440-1
• MDL number: MFCD00866530

Properties

• Quality Segment: 200
• SMILES string: C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=C(F)C(=O)NC2=O
• InChI: 1S/C9H11FN2O5/c1-3-5(13)6(14)8(17-3)12-2-4(10)7(15)11-9(12)16/h2-3,5-6,8,13-14H,1H3,(H,11,15,16)/t3-,5-,6-,8-/m1/s1
• InChI key: ZWAOHEXOSAUJHY-ZIYNGMLESA-N

Description

Biochem/physiol Actions

Doxifluridine is an antitumor agent efficient in tumors, cell lines or in fibroblasts transformed by H-ras or trk oncogenes. Possesses anticachectic activity which is independent of its antiproliferative activity.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)