F5631

Fucoidan from Fucus vesiculosus

Crude

• Synonym(s): Fucoidin
• CAS Number: 9072-19-9
• UNSPSC Code: 12352201
• NACRES: NA.25
• MDL number: MFCD00131109

Properties

• biological source: algae (Fucus Vesiculosus)
• Quality Segment: 200
• form: powder
• quality: Crude
• color: light yellow to brown
• solubility: H₂O: 10 mg/mL, clear to hazy, faintly yellow to brownish-yellow
• cation traces: Ca: ≤1%, Na: ≤ 8% (ICP)
• storage temp.: room temp

Description

General description

Fucoidan is a fucose-rich, sulfated polysaccharide isolated from several species of brown seaweed.

Application

Fucoidan from Fucus vesiculosus may be used as a biological response modifier and as a potential therapeutic agent with a wide range of biological activities. It may be used to study its pharmacokinetics, safety, efficacy and methods of delivery as a potential anticancer, anti-immune and anti-inflammatory agent. Fucoidan may be used to assess its potential and formulations for tissue engineering applications.

Biochem/physiol Actions

Studies of fucoidan have found it to have a broad variety of biological activities including antitumor and antiangogenic activities, immunomodulatory, anti-inflammatory, anticoagulant, antithrombotic, and antioxidant activities. Fucoidan induces macrophage activation with subsequently activates mitogen activated protein kinases (MAPKs) and results in natural killer cell proliferation. Fucoidan acts as a nonselective selectin blocker and has been shown to induce apoptosis and suppress angiogenesis.

Preparation Note

Prepared by a modification of the method of Black, W.A.P., et al., J. Sci. Food Agri., 3, 122 (1952).

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)