C8982

α-Cyano-4-hydroxycinnamic acid

suitable for MALDI-TOF MS

• Synonym(s): α-CCA, α-CHCA, α-Cyano, 4-HCCA, ACCA
• Linear Formula: HOC₆H₄CH=C(CN)CO₂H
• CAS Number: 28166-41-8
• Molecular Weight: 189.17
• UNSPSC Code: 12352106
• NACRES: NA.21
• PubChem Substance ID: 24893121
• EC Number: 248-879-1
• Beilstein/REAXYS Number: 3271427
• MDL number: MFCD00004204

Properties

• Product Name: α-Cyano-4-hydroxycinnamic acid, suitable for MALDI-TOF MS
• InChI key: AFVLVVWMAFSXCK-VMPITWQZSA-N
• InChI: 1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+
• SMILES string: OC(=O)\C(=C\c1ccc(O)cc1)C#N
• form: powder
• analyte chemical class(es): glycans, peptides, proteins
• mp: 245-250 °C (lit.)
• suitability: suitable for MALDI-TOF MS
• storage temp.: room temp
• Quality Level: 100

Description

Application

α-Cyano-4-hydroxycinnamic acid has been used as a matrix for MALDI-TOF MS (matrix assisted laser desorption ionization-time of flight mass spectrometry) analysis. The matrix has also been used for sample preparation.

General description

α-Cyano-4-hydroxycinnamic acid (CHCA) is specially purified and qualified as a matrix for peptide MALDI-MS (matrix assisted laser desorption ionization-mass spectrometry) calibration standards. CHCA enhances ionization of protein or peptide standards and samples in matrix assisted laser desorption ionization (MALDI) mass spectrometers.
It is also available as part of our ProteoMass^™ MALDI calibration kits (MS-CAL1 and MS-CAL3).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

ProteoMass is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H317
• pcodes: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1B
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves