A9771

Albumin–fluorescein isothiocyanate conjugate

protein bovine

• Synonym(s): FITC-albumin
• UNSPSC Code: 12352204
• eCl@ss: 42010201
• NACRES: NA.32
• MDL number: MFCD00282182

Properties

• biological source: protein from bovine
• Quality Segment: 200
• form: powder
• extent of labeling: ≥7 mol FITCmol albumin
• technique(s): ELISA: suitable
• solubility: 10 mM Tris pH 7.0: 10 mg/mL
• application(s): detection
• storage temp.: 2-8°C

Description

General description

Albumin makes up 60% of the plasma protein, which is produced by the liver. It regulates colloid osmotic pressure. Albumin is implicated in the transportation, distribution and metabolism of fatty acids, thyroid hormones and drugs. It reduces weight gain, blocks pulmonary edema, decreases ascites and lowers tissue edema.

Application

Albumin−fluorescein isothiocyanate conjugate has been used:

• as a control to compare the intracellular delivery efficiency of proteins with or without carrier
• for the fluorescent visualization of proteins and cells
• as a blocking agent in ELISA
• as a chemical for brain perfusion and fixation
• for in vivo capillary–epithelial permeability experiment
• for confocal microscopy of right ventricular (RV) vasculature in rats

Preparation Note

Prepared from crystallized and lyophilized albumin (A 4378).

Safety Information

• pictograms: GHS08
• signalword: Danger
• hcodes: H317,H334
• pcodes: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• Hazard Classifications: Resp. Sens. 1 - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable