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Merck

A9754

2-Amino-2-methyl-1,3-propanediol

≥99%

Synonym(s):

AMPD, Ammediol

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About This Item

Linear Formula:
(HOCH2)2C(NH2)CH3
CAS Number:
115-69-5
Molecular Weight:
105.14
UNSPSC Code:
12161700
NACRES:
NA.25
PubChem Substance ID:
24891493
EC Number:
204-100-7
Beilstein/REAXYS Number:
635708
MDL number:
MFCD00004678

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InChI key

UXFQFBNBSPQBJW-UHFFFAOYSA-N

InChI

1S/C4H11NO2/c1-4(5,2-6)3-7/h6-7H,2-3,5H2,1H3

SMILES string

CC(N)(CO)CO

vapor density

3.63 (vs air)

vapor pressure

~10 mmHg ( 152 °C)

assay

≥99%

form

crystalline

pH

10.5-11.5 (25 °C, 105.1 g/L)

useful pH range

7.8-9.7

pKa (25 °C)

8.8

bp

151 °C/10 mmHg (lit.)

Quality Level

300

mp

100-110 °C (lit.)

solubility

H2O: 100 mg/mL, clear to slightly hazy, colorless to very faintly yellow

application(s)

diagnostic assay manufacturing

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1 of 4

This Item
A6659A1911T1378
2-Amino-2-methyl-1,3-propanediol ≥99%

Sigma-Aldrich

A9754

2-Amino-2-methyl-1,3-propanediol

AMPSO ≥99% (titration)

Sigma-Aldrich

A6659

AMPSO

AMPSO sodium salt

Sigma-Aldrich

A1911

AMPSO sodium salt

Sigma 7-9® ≥99% (titration), powder or crystals

Sigma-Aldrich

T1378

Sigma 7-9®

assay

≥99%

assay

≥99% (titration)

assay

-

assay

≥99% (titration)

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

200

form

crystalline

form

crystalline

form

crystalline powder

form

crystalline

application(s)

diagnostic assay manufacturing

application(s)

diagnostic assay manufacturing

application(s)

diagnostic assay manufacturing

application(s)

clinical research
diagnostic assay manufacturing
life science and biopharma
sample preparation

pH

10.5-11.5 (25 °C, 105.1 g/L)

pH

-

pH

-

pH

10.5-12

solubility

H2O: 100 mg/mL, clear to slightly hazy, colorless to very faintly yellow

solubility

water: 0.333 g/mL, clear to slightly hazy, colorless

solubility

water: 0.33 g/mL, clear to slightly hazy, colorless

solubility

water: 0.667 g/mL, clear, colorless to faintly yellow

Application

Buffer component in a SDS-gradient gel electrophoresis system that separates polypeptides in the molecular weight range of 1500 to 100,000. Used as a spacer in isotachophoresis of proteins. Also used as a buffer for the determination of alkaline phosphatase activity.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

>212.0 °F

flash_point_c

> 100 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000507376
0000507375
0000507375
0000507376
0000503114

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Masahiro Fukuyama et al.
Frontiers in cell and developmental biology, 9, 590333-590333 (2021-08-20)
Current approaches for human hair follicle (HF) regeneration mostly adopt cell-autonomous tissue reassembly in a permissive murine intracorporeal environment. This, together with the limitation in human-derived trichogenic starting materials, potentially hinders the bioengineering of human HF structures, especially for the
Murugappan Sathappa et al.
Bio-protocol, 6(22) (2016-12-09)
Biological membranes are vital for diverse cellular functions such as maintaining cell and organelle structure, selective permeability, active transport, and signaling. The surface charge of the membrane bilayer plays a critical role in these myriad processes. For most biomembranes, the
Takayuki Yakura et al.
Chemical & pharmaceutical bulletin, 55(9), 1385-1389 (2007-09-11)
Dirhodium(II)-catalyzed C-H amination reaction of (S)-3-(tert-butyldimethylsilyloxy)-2-methylpropyl carbamate, which was easily prepared from methyl (S)-2-methyl-3-hydroxypropanoate, proceeded more smoothly than those of their 2-(methoxycarbonyl)propyl derivative to give the corresponding oxazolidinone in excellent yield. The resulting oxazolidinone was converted efficiently into both (R)-monoprotected
H Kikuchi et al.
The Tohoku journal of experimental medicine, 173(4), 391-397 (1994-08-01)
The method by MacQueen and Plaut was modified to devise simple microdetermination method of l-lactate which is applicable to deproteinized blood sample. Blood was deproteinized with addition of 25% (w/w) trichloroacetic acid (TCA), and 0.075 M 2-amino-2-methyl-1, 3-propanediole (AMPD) was
Karen M O'Connor et al.
Journal of pharmaceutical sciences, 91(10), 2271-2281 (2002-09-13)
Dissolution of diclofenac from compressed discs containing mixtures of a diclofenac salt and a basic excipient, in various w/w ratios, was examined. Two diclofenac salts, diclofenac deanol (DDNL) and diclofenac tert-butylamine, and the basic excipient 2-amino-2-methyl-1,3-propanediol (AMPD) were examined. Inclusion
View All Related Papers

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Product Information Sheet - A9754

Product Information Sheet

Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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