A6677

Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro

synthetic (organicorganic), ≥97% (HPLC), fibronectin binding inhibitor, powder

• Synonym(s): Arginyl-Glycyl-Asparagyl-Serinyl-Prolyl-Alaninyl-Serinyl-Serinyl-Lysyl-Proline, RGDSPASSKP
• Empirical Formula (Hill Notation): C₄₀H₆₈N₁₄O₁₆
• CAS Number: 91575-25-6
• Molecular Weight: 1001.05
• UNSPSC Code: 12352202
• PubChem Substance ID: 24891126
• NACRES: NA.77
• MDL number: MFCD00076453
• Form: powder
• Assay: ≥97% (HPLC)
• Biological source: synthetic (organic; organic)

Properties

• Product Name: Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro, ≥97% (HPLC)
• biological source: synthetic (organic; organic)
• Quality Segment: 200
• assay: ≥97% (HPLC)
• form: powder
• UniProt accession no.: P02751
• storage temp.: −20°C
• SMILES string: CC(NC(=O)C1CCCN1C(=O)C(CO)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(N)CCCNC(N)=N)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)N2CCCC2C(O)=O
• InChI: 1S/C40H68N14O16/c1-20(31(61)50-24(17-55)35(65)51-25(18-56)34(64)49-22(8-2-3-11-41)37(67)54-14-6-10-28(54)39(69)70)47-36(66)27-9-5-13-53(27)38(68)26(19-57)52-33(63)23(15-30(59)60)48-29(58)16-46-32(62)21(42)7-4-12-45-40(43)44/h20-28,55-57H,2-19,41-42H2,1H3,(H,46,62)(H,47,66)(H,48,58)(H,49,64)(H,50,61)(H,51,65)(H,52,63)(H,59,60)(H,69,70)(H4,43,44,45)
• InChI key: JMBLPSUDFRAOLU-UHFFFAOYSA-N
• Gene Information: human ... FN1(2335)

Description

Application

Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro has been used to test its effect on the adhesion of Hemophilus somnus in bovine brain endothelial cells.

Biochem/physiol Actions

Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro peptide comprises the RGD sequence and blocks β2-integrin-binding sites.

Inhibits fibronectin binding to fibroblasts.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)