A3515

Adenosine 2′,5′-diphosphate–Agarose

lyophilized powder

• UNSPSC Code: 41106500
• NACRES: NA.56
• MDL number: MFCD00161940

Properties

• form: lyophilized powder
• Quality Segment: 200
• extent of labeling: 1-5 μmol per mL
• matrix: cross-linked 4% beaded agarose
• matrix activation: cyanogen bromide
• matrix attachment: N-6
• matrix spacer: 8 atoms
• storage temp.: −20°C

Description

Application

Adenosine 2′,5′-diphosphate Agarose (2′,5′-ADP agarose) has been used to study NADPH-cytochrome P450 oxidoreductase (CPR), which plays an important role in the insecticide resistance of Anopheles gambiae (a major malaria vector). In particular, Anopheles gambiae CPR (AgCPR) displayed a decreased affinity to adenosine 2′,5′-phosphate when compared to human CPR (hCPR) determined by isothermal titration calorimetry. This may be important for the development of more advanced insecticides that selectively target mosquito CPR.

Physical form

Lyophilized powder stabilized with lactose

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)