96599

DL-4-Hydroxy-2-ketoglutaric acid lithium salt

≥90.0% (TLC)

• Synonym(s): 4-Hydroxy-2-oxoglutaric acid lithium salt, DL-KHG Li
• Empirical Formula (Hill Notation): C₅H₆O₆ · xLi⁺
• CAS Number: 1187-99-1
• Molecular Weight: 162.10 (free acid basis)
• MDL number: MFCD18382351
• UNSPSC Code: 12352106
• NACRES: NA.28
• Beilstein/REAXYS Number: 1780096
• Assay: ≥90.0% (TLC)
• Form: solid

Properties

• Quality Segment: 100
• assay: ≥90.0% (TLC)
• form: solid
• impurities: ≤15.0% water, 3.9-8.4% lithium (anhydrous basis)
• storage temp.: −20°C
• SMILES string: OC(CC(=O)C(=O)O)C(=O)O
• InChI: 1S/C5H6O6/c6-2(4(8)9)1-3(7)5(10)11/h2,6H,1H2,(H,8,9)(H,10,11)
• InChI key: WXSKVKPSMAHCSG-UHFFFAOYSA-N

Description

Biochem/physiol Actions

DL-4-Hydroxy-2-ketoglutaric acid (DL-KHG) is an enzyme substrate for GOT (glutamic oxalacetic aminotransferase) and 2-Keto-4-hydroxyglutarate aldolase, which catalyzes the reversible cleavage of 2-keto-4-hydroxyglutarate yielding pyruvate plus glyoxylate; DL-KHG has been used in mass spectrometry for the rapid analysis of negatively charged water-soluble cellular metabolites.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable