53557
FITC–DEAE–Dextran
average mol wt 3,000-6,000
Synonym(s):
FITC–DEAE–Dextran 4, Fluorescein isothiocyanate–Diethylaminoethyl–Dextran
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About This Item
NACRES:
NA.32
UNSPSC Code:
12352116
form
solid
Quality Level
mol wt
average mol wt 3,000-6,000
composition
nitrogen content, 2-5%
extent of labeling
0.001-0.020 mol/mol FITC glucose
fluorescence
λex 493 nm; λem 518 nm in 0.1 M Tris pH 8.0
Application
FITC-DEAE-Dextran 4 is a cationic fluorescent dextran that may be used to study cell processes such as cell permeability, phagocytosis and endocytosis and to study mechanisms of biomolecular delivery. FITC-DEAE-Dextran 4 may be use to compare selectivity versus neutral FITC-Dextran 4 or anionic FITC-CM-Dextran 4.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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J K Leypoldt et al.
Kidney international, 43(4), 837-844 (1993-04-01)
The influence of molecular charge on macromolecule transport during peritoneal dialysis was assessed by determining transperitoneal transport rates for fluorescent-labeled macromolecules (molecular radii from 15 to 40 A) that differed only in molecular charge: neutral dextran, anionic dextran sulfate and
Carrier and dose effects on the pharmacokinetics of T-0128, a camptothecin analogue-carboxymethyl dextran conjugate, in non-tumor- and tumor-bearing rats.
Harada M, Murata J, Sakamura Y, et al.
J. Controlled Release, 71, 71-86 (2001)
Reduced diffusion of charge-modified, conformationally intact anionic Ficoll relative to neutral Ficoll across the rat glomerular filtration barrier in vivo.
Axelsson J, Sverrisson K, Rippe A, et al.
American Journal of Physiology: Renal Physiology, 301, F708-F712 (2011)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 136085-5G | 04061832248745 |
| 53557-1G | 04061826643471 |