504-05A
Human Tracheal Epithelial Cells: HTEpC, adult
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About This Item
NACRES:
NA.81
UNSPSC Code:
41106514
Biological source:
human trachea (normal surface epithelium)
Growth mode:
Adherent
Morphology:
epithelial
Relevant disease(s):
cardiovascular diseases
biological source
human trachea (normal surface epithelium)
packaging
pkg of 500,000 cells
manufacturer/tradename
Cell Applications, Inc
growth mode
Adherent
karyotype
2n = 46
morphology
epithelial
technique(s)
cell culture | mammalian: suitable
relevant disease(s)
cardiovascular diseases
shipped in
dry ice
storage temp.
−196°C
General description
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HTEpC provide a useful model system to study all aspects of epithelial function and disease, particularly those related to airway viral infections, as well as tissue repair mechanisms, signaling changes and potential treatments relevant to lung injuries, mechanical and oxidative stress, pulmonary diseases and smoking.
HTEpC have been used in a study investigating the role of goblet cell hyperplasia, possibly mediated by the expression of SPDEF, to the pathogenesis of chronic pulmonary diseases (Park, 2007).
Characterization: the cells have a characteristic morphology consistent with an epithelial origin and are positive for epithelial cell marker cytokeratin 18.
HTEpC provide a useful model system to study all aspects of epithelial function and disease, particularly those related to airway viral infections, as well as tissue repair mechanisms, signaling changes and potential treatments relevant to lung injuries, mechanical and oxidative stress, pulmonary diseases and smoking.
HTEpC have been used in a study investigating the role of goblet cell hyperplasia, possibly mediated by the expression of SPDEF, to the pathogenesis of chronic pulmonary diseases (Park, 2007).
Characterization: the cells have a characteristic morphology consistent with an epithelial origin and are positive for epithelial cell marker cytokeratin 18.
Application
epithelial function, tissue repair, cell signaling, lung injury treatment, mechanical and oxidative stress tests, lung lubrication, humidity maintenance, cleaning of respiratory tract, testing of drugs, toxins and carcinogens, respiratory function
Biochem/physiol Actions
Trachea
Preparation Note
- 1st passage, >500,000 cells in Basal Medium containing 10% FBS & 10% DMSO
- Can be cultured at least 16 doublings
Please refer to the HTEpC Culture Protocol.
Other Notes
Basal Medium containing 10% FBS & 10% DMSO
Storage Class
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
No data available
Flash Point (°C)
No data available
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