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313M-1

Cytokeratin Cocktail (AE1 & AE3) Mouse Monoclonal Antibody

Name: Cytokeratin Cocktail (AE1 & AE3) Mouse Monoclonal Antibody
Brand: SIGMA

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About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

AE1 & AE3, monoclonal

Application:

IHC (p)

Citations:

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Properties

biological source

mouse

Quality Segment

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

AE1 & AE3, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (313M-14), vial of 0.5 mL concentrate (313M-15), bottle of 1.0 mL predilute (313M-17), vial of 1.0 mL concentrate (313M-16), bottle of 7.0 mL predilute (313M-18)

manufacturer/tradename

Cell Marque^®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG1κ

control

breast, colon, prostate, skin

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... KRT1(3848)

Description

General description

Anti-cytokeratin cocktail (AE1 & AE3) is a broad-spectrum keratin antibody cocktail. It is composed of mouse monoclonal antibody AE1 that recognizes acidic type I keratins and AE3 that reacts with basic type II keratins. Both clones were generated using epidermal keratin as immunogen. This antibody is useful for identifying cells of epithelial origin and detects most carcinomas of different primarysites. This antibody cocktail can cross-react with other intermediate filaments, such as glialfibrillary acidic protein, giving false-positive staining in glial tumors.