30070

Cysteamine

≥98.0% (RT)

• Synonym(s): β-Mercaptoethylamine, 2-Aminoethanethiol, 2-Mercaptoethylamine, Decarboxycysteine, MEA, Thioethanolamine
• Linear Formula: NH₂CH₂CH₂SH
• CAS Number: 60-23-1
• Molecular Weight: 77.15
• UNSPSC Code: 12352116
• NACRES: NA.25
• PubChem Substance ID: 57648397
• EC Number: 200-463-0
• Beilstein/REAXYS Number: 635649
• MDL number: MFCD00008196
• Assay: ≥98.0% (RT)

Properties

• Quality Segment: 200
• assay: ≥98.0% (RT)
• storage temp.: 2-8°C
• SMILES string: NCCS
• InChI: 1S/C2H7NS/c3-1-2-4/h4H,1-3H2
• InChI key: UFULAYFCSOUIOV-UHFFFAOYSA-N

Description

Application

Cysteamine is suitable for use:

• in the preparation of cysteamine modified gold nanoparticles (AuNP)
• in the fabrication of SU-8 microrods, where in, the amine group of cysteamine reacts with the unreacted epoxide rings present on the surface of the particles, thereby opening it and forming a covalent bond
• to enhance in vitro development of porcine oocytes matured and fertilized in vitro
• in a study to demonstrate the depletion effect of cysteamine on cystinotic leucocyte granular fractions of cystine by disulphide interchange
• as a radioprotector
• to administer subcutaneously in rats to study its blocking effect on somatostatin secretion without modifying the pancreatic insulin or glucagon content
• as a scavenger in electrophoretic gels (acetic acid/urea gels)

Biochem/physiol Actions

Cysteamine (β-mercaptoethylamine) depletes cystine from patient′s cells and there by regulates renal glomerular function and increases growth in them. Therefore, cysteamine is considered to be a potential therapeutic for nephropathic cystinosis.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves