This product is not ISO 17034 certified. Please see the following EDTA disodium salt which is ISO 27034 certified:
https://www.sigmaaldrich.com/product/sial/phr1068
E1644
Ethylenediaminetetraacetic acid disodium salt dihydrate
BioUltra, 98.5-101.5%
Synonym(s):
Disodium ethylenediaminetetraacetate dihydrate, EDTA disodium salt, EDTA-Na2, Edathamil, Edetate disodium salt dihydrate, Sequestrene Na2
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biological source
synthetic (organic)
Quality Level
product line
BioUltra
assay
98.5-101.5%
form
powder
reaction suitability
reagent type: chelator
impurities
≤0.005% Phosphorus (P), ≤0.05% NH3, ≤0.1% Insoluble matter
pH
4.0-6.0 (0.1 M in H2O)
mp
248 °C (dec.) (lit.)
solubility
H2O: 0.1 M, clear, colorless
cation traces
Al: ≤0.001%, Ca: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, Pb: ≤0.001%, Zn: ≤0.0005%
storage temp.
room temp
SMILES string
O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
InChI
1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2
InChI key
OVBJJZOQPCKUOR-UHFFFAOYSA-L
General description
Ethylenediaminetetraacetic acid (EDTA) is a substituted diamine and a chelator of metal ions. It has anticoagulant and antibacterial activity. EDTA is an inhibitor of metalloprotease. It evades the undesirable effects of ferric, cupric and manganic ions in bleaching. It blocks cellular division, chlorophyll synthesis and algal biomass production.
Application
Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.
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This Item | |||
|---|---|---|---|
| assay 98.5-101.5% | assay 98.5-101.5% (titration) | assay 99.0-101.0% | assay 99.0-101.0% |
| product line BioUltra | product line - | product line - | product line - |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| form powder | form powder | form crystals | form solid |
| mp 248 °C (dec.) (lit.) | mp 248 °C (dec.) (lit.) | mp 248 °C (dec.) (lit.) | mp 248 °C (dec.) (lit.) |
| pH 4.0-6.0 (0.1 M in H2O) | pH - | pH 4-5 (20 °C, 5%) | pH 4.0-6.0 (25 °C, 5%) |
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - STOT RE 2 Inhalation
target_organs
Respiratory Tract
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Modulation of matrix metalloproteinase activity by EDTA prevents posterior capsular opacification
Hazra S, et al.
Molecular Vision, 18, 1701-1701 (2012)
Accurate Results in the Clinical Laboratory: A Guide to Error Detection and Correction (2013)
Matthew R Miller et al.
Journal of biological methods, 2(3), e23-e23 (2015-10-13)
Over the past two decades, researchers have struggled to efficiently express foreign DNA in primary macrophages, impeding research progress. The applications of lipofection, electroporation, microinjection, and viral-mediated transfer typically result in disruptions in macrophage differentiation and function, low expression levels
Global Trade Item Number
| SKU | GTIN |
|---|---|
| E1644-100G | 04061833602041 |
| E1644-250G | 04061833602058 |
| E1644-1KG | 04061835544387 |
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Esiste con certificato 17034 ?
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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