75423

Vancomycin supplement

for Enterobacter spp., powder, pack of 5 vials, suitable for microbiology

• Synonym(s): Vancomycin hydrochloride
• Empirical Formula (Hill Notation): C₆₆H₇₅Cl₂N₉O₂₄ · xHCl
• CAS Number: 1404-93-9
• Molecular Weight: 1449.25 (free base basis)
• MDL number: MFCD00064593
• UNSPSC Code: 41171614
• NACRES: NA.85

Properties

• Quality Segment: 200
• agency: according to GB 4789.40-2016, according to ISO 22964:2017
• sterility: sterile
• form: powder
• shelf life: limited shelf life, expiry date on the label
• packaging: pack of 5 vials
• color: white
• application(s): environmental; food and beverages, microbiology
• storage temp.: 2-8°C
• suitability: Enterobacter spp.
• SMILES string: [Cl-].Clc1c2ccc(c1)[C@H]([C@@H]3NC(=O)[C@H](NC(=O)[C@@H]6NC(=O)[C@@H](NC(=O)[C@@H]([C@@H](c7cc(c(cc7)Oc8c(c(cc6c8)O2)O[C@@H]9O[C@@H]([C@H]([C@@H]([C@H]9O[C@@H]%10O[C@H]([C@H]([C@](C%10)(N)C)O)C)O)O)CO)Cl)O)NC(=O)[C@H]([N+H2]C)CC(C)C)CC(=O)N)c4cc(c(cc4)O)c
• InChI: 1S/C66H75Cl2N9O24.ClH/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92;/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95);1H/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-;/m0./s1
• InChI key: LCTORFDMHNKUSG-XTTLPDOESA-N

Description

General description

Vancomycin supplement is a microbiology-grade antibiotic supplement used torender culture media selective for certain Gram‑negative bacteria. It consists of vancomycin hydrochloride, a glycopeptideantibiotic with strong activity against Gram‑positive organisms but little activity against Gram‑negative bacteria. The supplement is intended to be added to appropriatebase media to inhibit accompanying Gram‑positive flora and thereby improve recovery and selective enrichment oftarget Gram‑negative species such asEnterobacter sakazakii (now Cronobacter spp.). ISO methodsrecommend this supplement for the selective enrichment of Enterobactersakazakii in food and environmental samples.

Application

Vancomycin supplement is primarily used as an antibiotic additive forselective enrichment media, especially in methods aligned with ISOrecommendations to detect Enterobacter sakazakii/Cronobacterspp. in powdered infant formula and related products. It has also been employedin selective media to investigate vancomycin‑resistant enterococci (VRE) in treated wastewater and other environmentalsamples, where defined concentrations of vancomycin are used to select forresistant populations while suppressing susceptible Gram‑positive bacteria

Other Notes

(per vial, sufficient for 1000 ml medium)
Vancomycin 10.00 mg

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Codes: H317,H334
• Precautionary Statements: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• Hazard Classifications: Resp. Sens. 1 - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): dust mask type N95 (US), Eyeshields, Faceshields, Gloves