46725

Salbutamol

VETRANAL^®, analytical standard

• Synonym(s): α-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-α,α′-diol, Albuterol
• Empirical Formula (Hill Notation): C₁₃H₂₁NO₃
• CAS Number: 18559-94-9
• Molecular Weight: 239.31
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329757226
• EC Number: 242-424-0
• Beilstein/REAXYS Number: 6405698
• MDL number: MFCD00148978

Properties

• grade: analytical standard
• Quality Segment: 100
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable
• application(s): clinical testing
• format: neat
• SMILES string: CC(C)(C)NCC(O)c1ccc(O)c(CO)c1
• InChI: 1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3
• InChI key: NDAUXUAQIAJITI-UHFFFAOYSA-N
• Gene Information: human ... ADRB2(154)

Description

General description

Standard for Supelco MIP SPE cartridges. For more information request Supelco Literature T407075, T706019, T706030, T706020. Salbutamol is classified under the β-agonist group of chemicals which are known to possess powerful pharmacological activities.

Application

Salbutamol may be used as a reference standard for the determination of salbutamol in:

• Fish plasma by solid phase extraction (SPE) followed by analysis using liquid chromatography combined with electrospray ionization triple quadrupole mass spectrometry (ESI-LC-QqQMS).
• Feed samples by ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) as well as supercritical fluid chromatography (SFC) with MS/MS.
• Pig hair by HPLC in combination with ESI-MS/MS.
• Water and swine feed by dual labeled time-resolved fluoroimmunoassay (TRFIA) using lanthanide ions-based fluorescent probes and HPLC equipped with ultraviolet (UV) detector.
• Treated wastewater by direct injection (DI) combined with UHPLC coupled to quadrupole-linear ion trap analyser (QqLIT-MS/MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

β₂-adrenoceptor agonist

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

sensitive to light

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Codes: H302,H317,H319,H412
• Precautionary Statements: P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1B
• Storage Class: 11 - Combustible Solids
• WGK: WGK 2
• PPE (personal protective equipment): dust mask type N95 (US), Eyeshields, Gloves