46232
Dipyron monohydrate
VETRANAL®, analytical standard
Synonym(s):
Metamizol, Methapyrone
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About This Item
Empirical Formula (Hill Notation):
C13H16N3NaO4S · H2O
CAS Number:
Molecular Weight:
351.35
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3865381
grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
clinical
forensics and toxicology
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
O.[Na+].CN(CS([O-])(=O)=O)C1=C(C)N(C)N(C1=O)c2ccccc2
InChI
1S/C13H17N3O4S.Na.H2O/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11;;/h4-8H,9H2,1-3H3,(H,18,19,20);;1H2/q;+1;/p-1
InChI key
UNZIDPIPYUMVPA-UHFFFAOYSA-M
Gene Information
human ... PTGS1(5742), PTGS2(5743)
General description
Metamizol is an active pharmaceutical ingredient with both analgesic and antipyretic effects, primarily used to relieve pain caused by neuritis and neuralgia.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Metamizol may be used as a reference standard for the determination of metamizol in pharmaceutical formulations by reversed-phase high-performance liquid chromatography (RP-HPLC).
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Repr. 2
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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Simultaneous Determination Of Metamizole, Thiamin And Pyridoxin In Multicomponent Tablet by RP-HPLC.
Chotimah C.
Journal of Food and Pharmaceutical Sciences, 2(3) (2014)
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This study aimed to compare the impact of testosterone and estrogen replacement therapy on mandibular bone density and bone-related markers. Forty male adult rats were randomly allocated to 4 experimental groups (n = 10/group): Sham (Control); Orchiectomy; Orchiectomy plus testosterone replacement; and
Tina Kirchner et al.
Mediators of inflammation, 2012, 849136-849136 (2012-04-07)
The formation of neutrophil extracellular traps (NETs) depends on the generation of reactive oxygen species (ROS). Previous studies revealed that both NADPH oxidase and myeloperoxidase (MPO) are required for NET release. However, the contribution of various ROS as well as
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 46232-250MG | 04061832346427 |