GF313
TGF- α Protein, Human Recombinant Animal Free
>98% (SDS-PAGE and HPLC), <0.1 μg/mg protein endotoxin (<1EU/μg)
Synonym(s):
Transforming growth factor alpha, TGFa, TGF alpha, EGF-like TGF, TGF type 1
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| Size/SKU | Availability | Price |
|---|---|---|
100 μg | Check Cart for Availability | $492.00 |
About This Item
UNSPSC Code:
12352202
NACRES:
NA.75
eCl@ss:
32160405
Assay:
>98% (SDS-PAGE and HPLC)
Recombinant:
expressed in E. coli
recombinant
expressed in E. coli
Quality Segment
assay
>98% (SDS-PAGE and HPLC)
impurities
<0.1 μg/mg protein endotoxin (<1EU/μg)
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
-10 to -25°C
General description
Product Source: E. coli
Transforming growth factor alpha (TGF-α) is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
Application
Research Category
Stem Cell Research
Stem Cell Research
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
Biochem/physiol Actions
Cross Reactivty
Chicken, Mouse, Rat
Chicken, Mouse, Rat
Physical form
Product is filtered through a 0.2 micron filter before lyophilization.
Recombinant animal free human TGF- α is manufactured using all non-animal reagents
Preparation Note
Store at -20°C for up to 6 months from date of receipt.
Analysis Note
Bioactivity assay: Determined by its ability to stimulate the proliferation of mouse Balb/c 3T3 cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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This Item | |||
|---|---|---|---|
| recombinant expressed in E. coli | recombinant expressed in E. coli | recombinant - | recombinant - |
| assay >98% (SDS-PAGE and HPLC) | assay >98% (SDS-PAGE and HPLC) | assay - | assay >98% (SDS-PAGE and HPLC) |
| storage temp. -10 to -25°C | storage temp. -10 to -25°C | storage temp. -10 to -25°C | storage temp. -10 to -25°C |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in dry ice |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
| impurities <0.1 μg/mg protein endotoxin (<1EU/μg) | impurities <0.1 μg/mg protein endotoxin (<1 EU/μg) | impurities <0.1 μg/mg protein endotoxin (<1 EU/μg) | impurities <0.1 μg/mg protein endotoxin (<1 EU/μg) |
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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