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Sigma-Aldrich

Goat Anti-Guinea Pig IgG Antibody, HRP conjugate

Chemicon®, from goat

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.46

biological source

goat

Quality Level

conjugate

peroxidase conjugate

antibody form

F(ab′)2 fragment of affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

species reactivity

guinea pig

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

shipped in

wet ice

target post-translational modification

unmodified

General description

Immunoglobulin G (IgG) is the most common type of antibody in the human serum. It exists in four isotypes IgG1, IgG2, IgG3, and IgG4. IgG is produced by the B cells. IgG structure contains four polypeptide chains with two identical heavy (H) chains and two identical λ light (L) chains. These chains are inter-linked by disulfide bonds.

Application

Goat Anti-Guinea Pig IgG Antibody, HRP conjugate has been used in immunoblot analysis and enzyme-linked immunosorbent assay (ELISA) (1:2000).

Biochem/physiol Actions

Immunoglobulin G (IgG) initiates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays an essential role in antibody-dependent cell-mediated cytotoxicity (ADCC). Maternal IgG is transferred to the fetus through the placenta that is crucial for protecting newborns against infectious diseases. Levels of IgG in severe acute respiratory syndrome coronavirus (SARS‐CoV)‐2 infected patients can be used as a potential tool to evaluate the severity and prognosis of coronavirus disease 2019 (COVID‐19).

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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T Hesari et al.
Archives of Razi Institute, 77(2), 739-745 (2022-10-27)
Immunization has been considered a successful global health program that saves many persons' lives each year. The vaccines reduce the risk of getting the disease by building immunity in the body. Therefore, the constant availability of essential vaccines is an
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Sechi S, et al.
Cells, 10, 2336-2336 (2021)
Pauravi J Gandhi et al.
Cells, 10(10) (2021-10-24)
Chronic pain is a debilitating condition involving neuronal dysfunction, but the synaptic mechanisms underlying the persistence of pain are still poorly understood. We found that the synaptic organizer glutamate delta 1 receptor (GluD1) is expressed postsynaptically at parabrachio-central laterocapsular amygdala
Ana Francisca Soares et al.
Journal of neuroscience research, 97(8), 1004-1017 (2019-05-03)
Diabetes impacts the central nervous system predisposing to cognitive decline. While glucose is the main source of energy fueling the adult brain, brain glycogen is necessary for adequate neuronal function, synaptic plasticity and memory. In this study, we tested the
Juan David Olivares-Hernández et al.
Neural plasticity, 2021, 9990166-9990166 (2021-09-28)
As a classical growth promoter and metabolic regulator, growth hormone (GH) is involved in development of the central nervous system (CNS). This hormone might also act as a neurotrophin, since GH is able to induce neuroprotection, neurite growth, and synaptogenesis

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