437692

α-Lipoic Acid

≥99% (by assay), antioxidant , solid

• Synonym(s): α-Lipoic Acid, DL-Thioctic Acid
• Empirical Formula (Hill Notation): C₈H₁₄O₂S₂
• CAS Number: 1077-28-7
• Molecular Weight: 206.33
• UNSPSC Code: 12352106
• NACRES: NA.77
• MDL number: MFCD00005474
• Assay: ≥99% (by assay)
• Form: solid
• Storage condition: OK to freeze

Properties

• Product Name: α-Lipoic Acid, α-Lipoic Acid, CAS 1077-28-7 is an oxidized form with antioxidant properties. Reduces renal lipid peroxidation in rats with cisplatin n-induced nephrotoxicity.
• Quality Segment: 200
• description: Merck USA index - 14, 9326
• assay: ≥99% (by assay)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: pale yellow
• solubility: ethanol: soluble, methanol: soluble
• shipped in: ambient
• storage temp.: 10-30°C
• SMILES string: S1SCCC1CCCCC(=O)O
• InChI: 1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)
• InChI key: AGBQKNBQESQNJD-UHFFFAOYSA-N

Description

General description

Oxidized form. Has antioxidant properties. Reported to effectively reduce renal lipid peroxidation in rats with cisplatin-induced nephrotoxicity. Acts as a growth factor for many bacteria and protozoa.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Reduce renal lipid peroxidation in rats with cisplatin-induced nephrotoxicity

Product does not compete with ATP.

Reversible: no

Other Notes

Somami, S. M., et al. 2000. Pharmacol. Toxicol. 86, 234.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

Safety Information

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H302,H315,H317,H319,H411
• pcodes: P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable