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Caffeine

Name: Caffeine
Brand: MM

≥99% (HPLC), central nervous system stimulant, solid

Synonym(s):

Caffeine, 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

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About This Item

Empirical Formula (Hill Notation):

C₈H₁₀N₄O₂

CAS Number:

58-08-2

Molecular Weight:

194.19

UNSPSC Code:

12352200

NACRES:

NA.77

MDL number:

MFCD00005758

Assay:

≥99% (HPLC)

Form:

solid

Storage condition:

OK to freeze

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Properties

Product Name

Caffeine, Trimethylated xanthine that acts as a potent central nervous system stimulant.

description

Merck USA index - 14, 1636

Quality Segment

100

assay

≥99% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

color

white

solubility

chloroform: 50 mg/mL

shipped in

ambient

storage temp.

10-30°C

SMILES string

[n]1(c2c(nc1)N(C(=O)N(C2=O)C)C)C

InChI

1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3

InChI key

RYYVLZVUVIJVGH-UHFFFAOYSA-N

Description

General description

Trimethylated xanthine that acts as a potent central nervous system stimulant. At higher doses, produces tachycardia and interferes with the uptake and storage of Ca²⁺by the sarcoplasmic reticulum in skeletal muscle. Prevents apoptosis and cell cycle effects induced by Camptothecin (Cat. No. 208925 ) and topotecan in HL-60 cells.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Potent central nervous system stimulant

Product does not compete with ATP.

Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Zhen, W., and Vaugha, A. T. 1995. Radiat. Res.141, 170.
Howell, L. L. 1993. Cancer Res.54, 4993.
Traganos, F., et al. 1993. Cancer Res.53, 4613.
Zahradnik, I., and Palade, P. 1993. Pflugers Arch. 424, 129.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

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Show Differences

1 of 1

This Item	C8960	1085003	W222402
Sigma-Aldrich 205548 Caffeine	Sigma-Aldrich C8960 Caffeine	USP 1085003 Caffeine	Sigma-Aldrich W222402 Caffeine
description Trimethylated xanthine that acts as a potent central nervous system stimulant.	description BioXtra	description United States Pharmacopeia (USP) Reference Standard	description anhydrous, 99%, FCC, FG
form solid	form powder	form -	form powder
assay ≥99% (HPLC)	assay -	assay -	assay 99%
manufacturer/tradename Calbiochem^®	manufacturer/tradename -	manufacturer/tradename USP	manufacturer/tradename -
Quality Level 100	Quality Level 200	Quality Level -	Quality Level 300, 400
storage temp. 10-30°C	storage temp. -	storage temp. -	storage temp. -
solubility chloroform: 50 mg/mL	solubility chloroform: 0.5 M, clear, colorless	solubility -	solubility H₂O: soluble 18.7 g/L at 16 °C

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 1

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