1.37003
Citric acid monohydrate
crystalline, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP
Synonym(s):
2-Hydroxypropane-1,2,3-tricarboxylic acid, Hydroxytricarballylic acid
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About This Item
Quality Segment
agency
BP, ChP, JP, Ph. Eur., USP
vapor pressure
<1 Pa ( 25 °C)
description
cryst. EMPROVE® EXPERT Ph Eur,BP,ChP,JP,USP
product line
EMPROVE® EXPERT
form
solid, crystalline
feature
RNase and DNase free
impurities
endotoxins, low
pH
1.85 (25 °C, 50 g/L in H2O)
pKa
(1) 3.13, (2) 4.76, (3) 6.4
mp
135-152 °C
transition temp
flash point 173.9 °C
solubility
880 g/L
density
1.54 g/cm3 at 20 °C
application(s)
liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical
storage temp.
15-25°C
SMILES string
OC(CC(O)(C(O)=O)CC(O)=O)=O.O
InChI
1S/C6H8O7.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);1H2
InChI key
YASYEJJMZJALEJ-UHFFFAOYSA-N
General description
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
Application
Due to its low microbial and endotoxin limits, Citric acid anhydrous Emprove® Expert is especially suitable for high-risk applications.
Legal Information
1 of 1
This Item | |||
|---|---|---|---|
| description crystalline, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP | description crystalline, EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, USP, FCC, E 330 | description powder, EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, JP, USP, FCC, E 330 | description European Pharmacopoeia (EP) Reference Standard |
| application(s) liquid formulation | application(s) liquid formulation | application(s) liquid formulation | application(s) pharmaceutical (small molecule) |
| agency BP, JP, USP, ChP, Ph. Eur. | agency BP, ChP, Ph. Eur., USP | agency BP, ChP, JP, Ph. Eur., USP | agency - |
| form crystalline, solid | form coarse powder, crystalline | form fine powder | form - |
| density 1.54 g/cm3 at 20 °C | density 1.54 g/cm3 at 20 °C | density 1.54 g/cm3 at 20 °C | density - |
| product line EMPROVE® EXPERT | product line EMPROVE® ESSENTIAL | product line EMPROVE® ESSENTIAL | product line - |
| solubility 880 g/L | solubility 880 g/L | solubility 880 g/L | solubility - |
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
345.0 °F - closed cup
flash_point_c
173.9 °C - closed cup
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