V-010

(±)-α-Tocopherol-D₆ (Vitamin E-D₆) solution

500 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₂₉H₄₄D₆O₂
• CAS Number: 113892-08-3
• Molecular Weight: 436.74
• UNSPSC Code: 41116107
• NACRES: NA.24
• MDL number: MFCD17015252

Properties

• grade: certified reference material
• Quality Segment: 300
• form: liquid
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 500 μg/mL in methanol
• technique(s): gas chromatography (GC): suitable, liquid chromatography (LC): suitable
• mp: -97.99 °C
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: O1[C@@](CCc2c1c(c(c(c2C([2H])([2H])[2H])O)C([2H])([2H])[2H])C)(CCC[C@@H](CCC[C@@H](CCCC(C)C)C)C)C
• InChI: 1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3/t21-,22-,29-/m1/s1/i5D3,7D3
• InChI key: GVJHHUAWPYXKBD-BCHQTGRQSA-N

Description

General description

It is the deuterated form of α-tocopherol, a form of fat-soluble vitamin E.

Snap-N-Spike^®
Snap-N-Shoot^®

Application

This stable-labeled Certified Spiking Solution^® is suitable for quantifying a-tocopherol in a variety of applications from diagnostic testing of Vitamin E deficiency to quality control testing of tocopherol-based dietary supplements or pharmaceutical preparations.

The certified reference material (CRM) in solution can also be used as an internal standard as follows:

• High-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) based combined analysis of retinol, α‐tocopherol, 25‐hydroxyvitamin D₂, and 25‐hydroxyvitamin in plasma samples of cardiovascular patients
• Simultaneous determination of 25-hydroxyvitamin-D₂ (25-OHD₂), 25-hydroxyvitamin-D₃ (25-OHD₃), and its 3-epimer (epi-25-OHD₃), retinol, and α-tocopherol in human serum samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
• Development of two ultra and high-performance liquid chromatographic methods, one coupled with atmospheric pressure chemical ionization and tandem mass spectrometric detector (UHPLC-APCI-MS/MS) and the other one with diode array detector (HPLC-DAD) to estimate fat-soluble vitamins A, D₃ and E in rice cereal-based baby food samples
• Multi-residue analysis of fat-soluble vitamins (FSVs)― retinol, 25(OH)D₂, 25(OH)D₃, epi-25(OH)D₃. and α-tocopherol in plasma and amniotic fluid samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS) following a single pre-treatment step

Features and Benefits

• Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
• Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
• Rigorously tested through real-time stability studies to ensure accuracy and shelf life
• Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
• Flame sealed under argon into ampoules for long-term shelf life
• Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H225,H301 + H311 + H331,H370
• pcodes: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• target_organs: Eyes
• Storage Class: 3 - Flammable liquids
• wgk: WGK 2
• flash_point_f: 49.5 °F - closed cup
• flash_point_c: 9.7 °C - closed cup