76153

PEGA resin

extent of labeling: ~0.4 mmol/g loading

• Synonym(s): Poly[acryloyl-bis(aminopropyl)polyethylene glycol]
• UNSPSC Code: 23151817
• NACRES: NA.22
• MDL number: MFCD00165212

Properties

• product line: PEGA
• form: crystals
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• extent of labeling: ~0.4 mmol/g loading
• impurities: 90% methanol
• particle size: 150-300 μm
• functional group: amine

Description

General description

PEGA resins are a hydrophilic acrylamide-PEG co-polymer providing a really extensive and more uniform swelling in a wide range of solvents (from water, methanol, ethanol to tetrahydrofuran, acetonitrile and toluene). The extreme swelling volume of this support in the standard peptide synthesis solvents DCM and DMF together with their good stability make them ideally suited for the batch as well as for continuous-flow syntheses.

Application

Polyacrylamide resin possessing long polyethylene glycol spacers giving extremely high swell resin may be used for:

• immobilizing enzymes in aqueous solution
• affinity purification of small-molecule binding proteins
• synthesis of peptide libraries with fluorescently labeled proteins

Packaging

Sold on basis of weight of dry resin.

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Gloves, type N95 (US)