543780

5′-Fluoro-2′-hydroxy-3′-nitroacetophenone

98%

• Linear Formula: FC₆H₂(OH)(NO₂)COCH₃
• CAS Number: 70978-39-1
• Molecular Weight: 199.14
• NACRES: NA.22
• PubChem Substance ID: 24878711
• UNSPSC Code: 12352100
• MDL number: MFCD03094007
• Assay: 98%

Properties

• Quality Segment: 100
• assay: 98%
• mp: 87-90 °C (lit.)
• functional group: fluoro, ketone, nitro
• SMILES string: CC(=O)c1cc(F)cc(c1O)[N+]([O-])=O
• InChI: 1S/C8H6FNO4/c1-4(11)6-2-5(9)3-7(8(6)12)10(13)14/h2-3,12H,1H3
• InChI key: YVTPUCHIOSGVSH-UHFFFAOYSA-N

Description

General description

5′-Fluoro-2′-hydroxy-3′-nitroacetophenone, also known as 1-(5-fluoro-2-hydroxy-3-nitrophenyl)ethanone, is an aromatic hydroxy ketone. It can be synthesized from 5-fluoro-2-hydroxy-acetophenone via nitration.

Application

5′-Fluoro-2′-hydroxy-3′-nitroacetophenone may be used to prepare 1-(3-amino-5-fluoro-2-hydroxyphenyl)ethanone via catalytic hydrogenation.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Codes: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): dust mask type N95 (US), Eyeshields, Gloves