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SAE0073

Sigma-Aldrich

Saponin

Synonym(s):

Surfactant Saponin

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About This Item

EC Number:
UNSPSC Code:
12161902
NACRES:
NA.21

description

non-ionic

Quality Level

composition

Sapogenin content, 20-35%

technique(s)

HPLC: suitable
LC/MS: suitable
protein quantification: suitable

sulfated ash

≤10%

Application

Saponins has been used to permeabilize dendritic cells (DCs) for intracellular staining with antibodies.

Biochem/physiol Actions

Saponins are associated with many biological and pharmacological activities. It is known to stimulate immune response in mammals. Saponins possesses antiviral, antifungal, antitumor, anti-inflammatory, hypoglycemic and hypocholesterolemic effects. It is a potent hemolytic, when injected intravaneously. It is also useful as a surfactant to enhance penetration of proteins and other macromolecules through cell membranes. Saponins have also been used as adjuvants for vaccines.

Packaging

10, 25 g in poly bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Flavia Radogna et al.
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Gotoh K, et al.
Cell Reports, 25(7), 1800-1815 (2018)
Sónia A Pinho et al.
The FEBS journal, 289(17), 5198-5217 (2022-02-26)
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