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C1159

L-Cycloserine

≥95% (TLC), ketosphinganine synthetase inhibitor, powder

Synonym(s):

(S)-4-Amino-3-isoxazolidone

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About This Item

Empirical Formula (Hill Notation):
C3H6N2O2
CAS Number:
339-72-0
Molecular Weight:
102.09
NACRES:
NA.77
PubChem Substance ID:
24278296
eCl@ss:
32160406
UNSPSC Code:
12352202
EC Number:
206-427-0
MDL number:
MFCD00064324
Beilstein/REAXYS Number:
80799
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Product Name

L-Cycloserine,

assay

≥95% (TLC)

Quality Segment

200

form

powder

mp

146 °C

solubility

H2O: 50 mg/mg protein

storage temp.

−20°C

SMILES string

N[C@H]1CONC1=O

InChI

1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m0/s1

InChI key

DYDCUQKUCUHJBH-REOHCLBHSA-N

Biochem/physiol Actions

Blocks sphingosine biosynthesis by inhibition of ketosphinganine synthetase. Cytotoxicity toward neuroblastoma and medulloblastoma cells mediated by suppression of ganglioside synthesis.
L-cycloserine is a potent inhibitor of serine palmitoyltransferase, the first step of sphingolipid synthesis.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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