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Key Documents

C1905000

Chlorpropamide

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

1-(p-Chlorobenzenesulfonyl)-3-propylurea

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About This Item

Empirical Formula (Hill Notation):
C10H13ClN2O3S
CAS Number:
Molecular Weight:
276.74
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

chlorpropamide

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1

InChI

1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)

InChI key

RKWGIWYCVPQPMF-UHFFFAOYSA-N

Gene Information

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Chlorpropamide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Pictograms

Health hazardExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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The chlorpropamide alcohol flush.
P G Wiles et al.
Clinical science (London, England : 1979), 67(4), 375-381 (1984-10-01)
[Flush induced by chlorpropamide-alcohol (CAF): a genetic marker of diabetes mellitus or an undesirable effect of the drug?].
J Sabán et al.
Revista clinica espanola, 176(3), 107-111 (1985-02-01)
Jing Li et al.
Critical care medicine, 42(12), e734-e740 (2014-11-18)
Cooling following cardiac arrest can improve survival significantly. However, delays in achieving target temperature may decrease the overall benefits of cooling. Here, we test whether lipid emulsion, a clinically approved drug reported to exert cardioprotection, can rescue heart contractility in
Chlorpropamide--alcohol flush: the case in favour.
C Johnston et al.
Diabetologia, 26(1), 1-5 (1984-01-01)
D C Klonoff
The American journal of medicine, 84(1), 33-38 (1988-01-01)
Clinical and metabolic features of chlorpropamide toxicity are described in two patients with diabetes mellitus and accidental chlorpropamide overdosage. Elevated serum insulin levels were found during hypoglycemia in both patients. The world's literature was reviewed for other cases of chlorpropamide

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