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286427

Sigma-Aldrich

L-Leucinamide hydrochloride

99%

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About This Item

Linear Formula:
(CH3)2CHCH2CH(NH2)CONH2·HCl
CAS Number:
Molecular Weight:
166.65
Beilstein:
4237021
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

99%

optical activity

[α]25/D +10°, c = 5 in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

254-256 °C (lit.)

application(s)

peptide synthesis

SMILES string

Cl.CC(C)C[C@H](N)C(N)=O

InChI

1S/C6H14N2O.ClH/c1-4(2)3-5(7)6(8)9;/h4-5H,3,7H2,1-2H3,(H2,8,9);1H/t5-;/m0./s1

InChI key

VSPSRRBIXFUMOU-JEDNCBNOSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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[Leucinamide specific cytosol leucine aminopeptidase].
T Kanno
Rinsho byori. The Japanese journal of clinical pathology, 30(5), 502-506 (1982-05-01)
Determination of the enantiomers of ketoprofen in blood plasma by ion-pair extraction and high-performance liquid chromatography of leucinamide derivatives.
S Björkman
Journal of chromatography, 414(2), 465-471 (1987-03-06)
A conductometric method for the assay of amidase and peptidase activities.
C R Hill et al.
Analytical biochemistry, 120(1), 165-175 (1982-02-01)
Andrew R Conrad et al.
The journal of physical chemistry. A, 115(34), 9676-9681 (2011-05-12)
Rotational spectra were recorded for two isotopic species of two conformers of the amide derivative of leucine in the range of 10.5-21 GHz and fit to a rigid rotor Hamiltonian. Ab initio calculations at the MP2/6-311++G(d,p) level identified the low
Claudio Jösch et al.
Biological chemistry, 384(2), 213-218 (2003-04-05)
Cysteinylglycine hydrolysis is a step in the metabolism of glutathione and glutathione S-conjugates. We had previously observed that in rat liver the enzymatic activity is predominantly located in the cytosol. Here we demonstrate that cytosolic leucyl aminopeptidase (EC 3.4.11.1) is

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