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P1134

Sigma-Aldrich

Porphobilinogen

powder

Synonym(s):

5-(Aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propanoic acid

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About This Item

Empirical Formula (Hill Notation):
C10H14N2O4
CAS Number:
487-90-1
Molecular Weight:
226.23
Beilstein:
220051
EC Number:
207-666-3
MDL number:
MFCD00005224
UNSPSC Code:
12352204
PubChem Substance ID:
24898159
NACRES:
NA.83

Assay

≥96% (HPLC)

Quality Level

200

form

powder

solubility

1 M NH4OH: 10 mg/mL

storage temp.

−20°C

SMILES string

NCc1[nH]cc(CCC(O)=O)c1CC(O)=O

InChI

1S/C10H14N2O4/c11-4-8-7(3-10(15)16)6(5-12-8)1-2-9(13)14/h5,12H,1-4,11H2,(H,13,14)(H,15,16)

InChI key

QSHWIQZFGQKFMA-UHFFFAOYSA-N

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Biochem/physiol Actions

Intermediate in the biosynthesis of heme.

Preparation Note

Enzymatically prepared.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Chinna Ayya P Swamy et al.
Chemical communications (Cambridge, England), 49(10), 993-995 (2012-12-21)
Facile synthesis of two new dimesitylboryl appended BODIPYs is reported. The two dyads have similar fluorescent chromophores but differ in their molecular conformations. They exhibit dual fluorescence, intramolecular energy transfer between boryl and BODIPY chromophores and different fluorescence responses (emission
Marco Grossi et al.
The Journal of organic chemistry, 77(20), 9304-9312 (2012-09-26)
The tetraarylazadipyrromethene chromophore class has gained increasing attention in the past decade for a diverse set of scientific interests and applications. The most direct synthetic route available for their generation is heating of 4-nitro-1,3-diarylbutan-1-ones with an ammonium source in an
Longhou Fang et al.
The Journal of clinical investigation, 121(12), 4861-4869 (2011-11-23)
Oxidative modification of LDL is an early pathological event in the development of atherosclerosis. Oxidation events such as malondialdehyde (MDA) formation may produce specific, immunogenic epitopes. Indeed, antibodies to MDA-derived epitopes are widely used in atherosclerosis research and have been
Bingshuai Wang et al.
Chemical communications (Cambridge, England), 49(10), 1014-1016 (2012-12-22)
We have developed a new reversible fluorescence probe MPhSe-BOD for the redox cycle process between hypochlorous acid and hydrogen sulfide in solution and in living cells. Confocal microscopy imaging using RAW264.7 cell lines shows that the probe has good cell
Xinfu Zhang et al.
The Journal of organic chemistry, 77(1), 669-673 (2011-11-25)
In the orignial 1,3,5,7-tetraphenyl aza-BODIPY, replacing the phenyl rings with thiophene achieved significant bathochromic shifts. One of the target molecules, DPDTAB, emitting strong NIR fluorescence with a quantum yield of 0.46 in acetonitrile, is a very competitive NIR fluorophore.
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