COV434

7071909, human ovary, Polygonal & fusiform

• Synonym(s): COV-434 Cells
• UNSPSC Code: 41106514

Properties

• Product Name: COV434, NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA., 07071909
• biological source: human ovary
• packaging: tube of 5 μg 07071909-DNA-5UG; pkg of vial of cells 07071909-1VL
• growth mode: Adherent
• karyotype: Modal chromosome no. 47 (46 - 47)
• morphology: Polygonal & fusiform
• products: Not specified
• receptors: Not specified
• technique(s): cell culture | mammalian: suitable
• relevant disease(s): cancer
• shipped in: dry ice
• storage temp.: −196°C

Description

Cell Line Origin

Human ovarian granulosa tumour

Cell Line Description

Human ovarian granulosa tumour cell line established from a solid primary tumour.

Application

COV434 has been used to study:

• the effect of 17β-estradiol on granulosa cell tumor growth, migration and invasion
• if mutant p53 (inactivatible R248Q hotspot mutation) works as a cancer-specific drug target
• the expression of TLR (toll-like receptor) and its function in the cell line

Culture Medium

DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS)

Subculture Routine

Split confluent cultures 1:2 to 1:5 i.e. seeding at 2-4x10,000 cells/cm² using trypsin/EDTA; 5% CO₂; 37°C.

Other Notes

Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.