The application of ion-pairing reagents as mobile phase additives ensures the elution of ionic and highly polar substances on reversed phase HPLC columns. The purity of mobile phase additives is of foremost significance for their successful utilization. Sigma-Aldrich offers a huge variety of tailor-made reagents for anionic (quaternary ammonium and phosphonium salts) and cationic (alkanesulfonates) separations. All mobile phase additives are investigated thoroughly with special regard to the requirements of modern reversed phase HPLC:
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Archives of pharmacal research, 37(11), 1416-1425 (2013-12-18)
Chronic hepatitis B virus (HBV) infection may lead to liver cirrhosis and hepatocellular carcinoma, but few drugs are available for its treatment. Acyclic nucleoside phosphonates (ANPs) have remarkable antivirus activities but are not easily absorbed from the gastrointestinal tract and
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