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341272

Sigma-Aldrich

Anti-Factor B Goat pAb

liquid, Calbiochem®

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

biological source

goat

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human

manufacturer/tradename

Calbiochem®

availability

not available in Canada

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

isotype

IgG

shipped in

ambient

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CFB(629)

General description

Goat polyclonal antibody supplied as undiluted serum. Recognizes Factor B.
Recognizes Factor B.
This Anti-Factor B Goat pAb is validated for use in Immunoelectrophoresis, Radial Immunodiffusion, Ouchterlony for the detection of Factor B.

Immunogen

Human
purified, human factor B

Application

Immunoelectrophoresis (see comments)

Radial Immunodiffusion (see comments)

Ouchterlony (≥ undiluted)

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

This antibody has also been reported to work for immunoelectrophoresis and radial immunodiffusion. Variables associated with assay conditions will dictate the proper working dilution.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Anna M Blom et al.
Journal of clinical immunology, 36(5), 517-527 (2016-05-06)
Autoantibodies termed C3-nephritic factor (C3NeF), which stabilize convertases of the alternative complement pathway, often stimulate autoinflammatory diseases. However, knowledge about analogous autoantibodies acting on the classical pathway (C4NeF) is limited to a few reports, which indicate association with kidney dysfunction
C Duehrkop et al.
Laboratory animals, 48(2), 143-154 (2014-03-04)
Prolonged ischemia of skeletal muscle tissue, followed by reperfusion, leads to ischemia/reperfusion injury (IRI), which is a feared local and systemic inflammatory reaction. With respect to the 3Rs, we wanted to determine which parameters for assessment of IRI require a
Claudia Duehrkop et al.
PloS one, 8(8), e72059-e72059 (2013-08-31)
Ischemia/reperfusion injury of lower extremities and associated lung damage may result from thrombotic occlusion, embolism, trauma, or surgical intervention with prolonged ischemia and subsequent restoration of blood flow. This clinical entity is characterized by high morbidity and mortality. Deprivation of
Diana Pauly et al.
Cell reports, 29(9), 2835-2848 (2019-11-28)
Complement dysregulation is a feature of many retinal diseases, yet mechanistic understanding at the cellular level is limited. Given this knowledge gap about which retinal cells express complement, we performed single-cell RNA sequencing on ∼92,000 mouse retinal cells and validated
Filippo Mori et al.
Frontiers in immunology, 15, 1334151-1334151 (2024-06-26)
Complement factor H (FH) is a major regulator of the complement alternative pathway, its mutations predispose to an uncontrolled activation in the kidney and on blood cells and to secondary C3 deficiency. Plasma exchange has been used to correct for

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