This product is tested by silver nitrate titration. The method is considered proprietary, the link below describes the general principle and offers a basic protocol:
https://www.canterbury.ac.nz/media/documents/science-outreach/chloride_volhard.pdf
Please refer to the literature for sodium hydroxide methods. The reference below may be helpful.
https://www.sciencedirect.com/science/article/abs/pii/B9780124115187000056
P51559
Propionyl chloride
98%
Synonym(s):
Chloro ethyl ketone, Ethyl chloroform, Propionic acid chloride, Prorionyl chloride
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About This Item
Linear Formula:
CH3CH2COCl
CAS Number:
Molecular Weight:
92.52
Beilstein:
385632
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Assay:
98%
Pricing and availability is not currently available.
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vapor density
3.2 (vs air)
Quality Level
Assay
98%
refractive index
n20/D 1.404 (lit.)
bp
77-79 °C (lit.)
mp
−94 °C
density
1.059 g/mL at 25 °C (lit.)
SMILES string
CCC(Cl)=O
InChI
1S/C3H5ClO/c1-2-3(4)5/h2H2,1H3
InChI key
RZWZRACFZGVKFM-UHFFFAOYSA-N
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General description
Propionyl chloride is an important chemical intermediate used to synthesize various propionic acid derivatives.
Application
Propionyl chloride can be used as an acylating agent:
It can also be used:
- To convert anisole to 4-methoxypropiophenone and 2-methoxynaphthalene to 1-propio-2-methoxynaphthalene in the presence of Indium(III) chloride (InCl3) impregnated mesoporous Si-MCM-41 catalyst.[1]
It can also be used:
- For chlorination in the presence of sulfuryl chloride and peroxides to form α-chloropropionyl chloride and β-chloropropionyl chloride.[2]
- In reaction with (hydroxypropyl)cellulose to form the propanoate ester, [(propionyloxy)propyl]cellulose.[3]
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
Supplementary Hazards
Storage Class Code
3 - Flammable liquids
WGK
WGK 1
Flash Point(F)
42.8 °F - closed cup
Flash Point(C)
6 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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How to do assy by titration with naoh solution
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