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A43804

Sigma-Aldrich

2-Amino-1-butanol

97%

Synonym(s):

(RS)-2-Amino-1-butanol, (±)-2-Amino-1-butanol, 1-(Hydroxymethyl)propylamine, 1-Hydroxy-sec-butylamine, 2-Amino-1-butanol, 2-Amino-1-hydroxybutane, 2-Aminobutyl alcohol

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About This Item

Linear Formula:
C2H5CH(NH2)CH2OH
CAS Number:
96-20-8
Molecular Weight:
89.14
EC Number:
202-488-2
MDL number:
MFCD00008095
UNSPSC Code:
12352100
PubChem Substance ID:
24890854
NACRES:
NA.22
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Assay

97%

form

liquid

refractive index

n20/D 1.4510 (lit.)

bp

176-178 °C (lit.)

mp

-2 °C (lit.)

density

0.943 g/mL at 25 °C (lit.)

SMILES string

CCC(N)CO

InChI

1S/C4H11NO/c1-2-4(5)3-6/h4,6H,2-3,5H2,1H3

InChI key

JCBPETKZIGVZRE-UHFFFAOYSA-N

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Related Categories

Signal Word

Danger

Hazard Statements

H302,H314,H410

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

188.6 °F - closed cup

Flash Point(C)

87 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0001451235
1451235V
1396061V
1451235
1377552

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2-Amino-2-methyl-1-propanol BioUltra, ≥99.0% (GC)

Sigma-Aldrich

08578

2-Amino-2-methyl-1-propanol

Potassium methylate (30-35% solution in methanol) for synthesis

Sigma-Aldrich

8.14222

Potassium methylate

M L Ancelin et al.
Analytical biochemistry, 199(2), 203-209 (1991-12-01)
A rapid, convenient, and efficient method is presented to measure phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol biosynthesis from [3H]choline, [3H]ethanolamine, and [3H]inositol, respectively. After incubation of the cells in 96-multi-well dishes with the appropriate radioactive precursor, cells were lysed with water and
Determination of optical purity by high-performance liquid chromatography of compounds of pharmaceutical interest.
G Gamberini et al.
Il Farmaco; edizione pratica, 43(11), 357-363 (1988-11-01)
R Ragonese et al.
Journal of pharmaceutical and biomedical analysis, 27(6), 995-1007 (2002-02-12)
Box-Behnken experimental designs do not appear to be extensively used in optimisation of analytical methods using capillary electrophoresis (CE). This paper describes the use of the Box-Behnken experimental design to optimise the factors affecting the separation of ethambutol hydrochloride (EB)
Georgi M Dobrikov et al.
European journal of medicinal chemistry, 48, 45-56 (2011-12-14)
The synthesis of 47 structurally diverse compounds incorporating the (R)-2-amino-1-butanol motif has been realized. Ten of these compounds were found to exhibit in vitro specific activity against Mycobacterium tuberculosis H37Rv in a MIC range of 0.65 μM-14.03 μM. Five of the most active
H J Vial et al.
Biochemical pharmacology, 33(17), 2761-2770 (1984-09-01)
A number of choline and ethanolamine analogs were evaluated as inhibitors of P. falciparum growth in vitro. 1-Aziridineethanol, DL-2-amino-1,3-propranediol and D- or L-2-amino-1-butanol were the most efficient inhibitors of parasite multiplication, with an IC50 of 50-80 microM, whereas numerous other
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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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