549835
2,4,6-Tris(dimethylamino)-1,3,5-triazine
96%
Synonym(s):
Altretamine, Hexamethylmelamine
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About This Item
Empirical Formula (Hill Notation):
C9H18N6
CAS Number:
Molecular Weight:
210.28
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
96%
mp
171-175 °C (lit.)
functional group
amine
SMILES string
CN(C)c1nc(nc(n1)N(C)C)N(C)C
InChI
1S/C9H18N6/c1-13(2)7-10-8(14(3)4)12-9(11-7)15(5)6/h1-6H3
InChI key
UUVWYPNAQBNQJQ-UHFFFAOYSA-N
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General description
2,4,6-Tris(dimethylamino)-1,3,5-triazine exhibits antitumor activity.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 20(4), 343-344 (2003-07-05)
To investigate the best first-line chemotherapy regimen for the treatment of advanced epithelial ovarian cancer (AEOC), the efficacy of three chemotherapy regimens for treatment of the patients with AEOC in our hospital during Jan. 1992-Jan. 1999 was retrospectively analyzed. The
M Hariharan et al.
Journal of microencapsulation, 19(1), 95-109 (2002-01-29)
Biodegradable poly(D,L-lactic acid) (PLA) microspheres containing hexamethylmelamine (HMM) were developed for potential use in chemoembolization and intraperitoneal implantation. The emulsion-solvent-evaporation/extraction method was used to prepare 15 formulations with different drug/polymer ratios, solvent compositions and emulsifer concentrations in the continuous aqueous
Peter Dornan et al.
Chemical communications (Cambridge, England), (31)(31), 3645-3647 (2008-07-31)
A novel method for the cyclotrimerization of dimethylcyanamide to form hexamethylmelamine has been developed using an aluminium amide catalyst; detailed DFT modelling of the catalytic cycle supports a triple insertion, nucleophilic ring closure, deinsertion mechanism.
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