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479160

Sigma-Aldrich

(R)-(+)-4-Hydroxy-2-pyrrolidinone

97%

Synonym(s):

(R)-β-Hydroxy-γ-butyrolactam

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About This Item

Empirical Formula (Hill Notation):
C4H7NO2
CAS Number:
22677-21-0
Molecular Weight:
101.10
Beilstein:
1524193
MDL number:
MFCD00273364
UNSPSC Code:
12352005
PubChem Substance ID:
24871603
NACRES:
NA.22

Quality Level

100

Assay

97%

optical activity

[α]23/D +43°, c = 1 in ethanol

mp

156-159 °C (lit.)

SMILES string

O[C@H]1CNC(=O)C1

InChI

1S/C4H7NO2/c6-3-1-4(7)5-2-3/h3,6H,1-2H2,(H,5,7)/t3-/m1/s1

InChI key

IOGISYQVOGVIEU-GSVOUGTGSA-N

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKBZ1072V
MKBQ7264V
MKBP3761V
MKBN9565V
MKBL8897V

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G Di Silvestro et al.
Journal of pharmaceutical sciences, 82(7), 758-760 (1993-07-01)
The phase diagram of (R)- and (S)-4-hydroxy-2-pyrrolidone presents a conglomerate in the racemic mixture. The enthalpy of melting extrapolated by the Schröder-van Laar-Le Chatelier equation [change in enthalpy (delta H) = 28410 J/mol; melting temperature (TA) = 429.9 K; solidus

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