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L6882

Sigma-Aldrich

D-Luciferin sodium salt

luminescent, ≥98% (HPLC), lyophilized powder

Synonym(s):

(S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic acid sodium salt, 4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid sodium salt, Firefly luciferin sodium salt

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About This Item

Empirical Formula (Hill Notation):
C11H7N2NaO3S2
CAS Number:
103404-75-7
Molecular Weight:
302.30
MDL number:
MFCD00044938
UNSPSC Code:
12352204
PubChem Substance ID:
24896446
NACRES:
NA.32

product name

D-Luciferin sodium salt, lyophilized powder, synthetic

biological source

synthetic

Quality Level

200

Assay

≥98% (HPLC)

form

lyophilized powder

solubility

H2O: soluble

fluorescence

λex 328 nm; λem 532 nm in H2O

storage temp.

−20°C

SMILES string

[Na+].Oc1ccc2nc(sc2c1)C3=N[C@H](CS3)C([O-])=O

InChI

1S/C11H8N2O3S2.Na/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16;/h1-3,7,14H,4H2,(H,15,16);/q;+1/p-1/t7-;/m1./s1

InChI key

LILQLBIQROYWIA-OGFXRTJISA-M

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General description

D-Luciferin is mainly produced in bioluminescent organisms. It can simply circulate across the blood testis barrier, blood brain barrier and the blood placenta barrier. This small molecule is sensitive to light and oxygen. D-Luciferin is also sensitive to moisture in its powder form.

Application

D-Luciferin sodium salt has been used as a substrate in luciferin−luciferase chemiluminescence assay to determine ATP levels.
Substrate for firefly luciferase with a Km of approx 2 μM.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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