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Key Documents

E7153

Sigma-Aldrich

Anti-phospho-ERK5 (pThr218/pTyr220) antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

Synonym(s):

Anti-BMK1

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About This Item

EC Number:
MDL number:
UNSPSC Code:
12352203
NACRES:
NA.44

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

human

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... MAPK7(5598)

General description

Extracellular Signal-Regulated Kinases (ERKs) are proteins that belong to mitogen-activated protein kinase superfamily (MAPK) and have a pivotal role in cell cycle, differentiation, transcription and learning and memory through signal transduction in the cytoplasm and the nucleus. ERK5 MAP kinase cascade has a crucial functions like- induction of special form of cardiac hypertrophy, enhanced neuronal survival and early steps of muscle cell differentiation. Anti-phospho-ERK5 (pThr218/pTyr220) antibody can be used in immunostaining. Rabbit anti- phospho-ERK5 (pThr218/pTyr220) antibody reacts specifically with ERK5 (88 kD) of human.

Immunogen

Synthetic phosphopeptide derived from the region of human ERK5 that contains threonine 218 and tyrosine 220. This sequence is conserved in human and mouse.

Application

Each vial contains enough material for 10 blots. The end user should determine the correct working dilution for their process.

Physical form

Solution in Dulbecco′s PBS, pH 7.3, with 50% glycerol, 1 mg/ml BSA and ≤ 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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