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Key Documents

07-226

Sigma-Aldrich

Anti-TrkC Antibody

Upstate®, from goat

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

goat

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, rat, mouse

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... OR4K13(390433)

Immunogen

Extracellular domain of rat TrkC receptor, corresponding to amino acid residues 1-429

Application

Detect TrkC using this Anti-TrkC Antibody validated for use in WB.
Research Category
Neuroscience
Research Sub Category
Vesicular Trafficking

Neurodegenerative Diseases

Target description

145kDa

Physical form

Format: Purified
Protein G Chromatography

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Support of trigeminal sensory neurons by nonneuronal p75 neurotrophin receptors.
Lixin Fan, Saulius Girnius, Bruce Oakley
Brain research. Developmental brain research null
Neurotrophin receptor TrkC is an entry receptor for Trypanosoma cruzi in neural, glial, and epithelial cells.
Weinkauf, C; Salvador, R; Pereiraperrin, M
Infection and Immunity null
E J Huang et al.
Development (Cambridge, England), 126(10), 2191-2203 (1999-04-20)
Animals lacking neurotrophin-3 (NT-3) are born with deficits in almost all sensory ganglia. Among these, the trigeminal ganglion is missing 70% of the normal number of neurons, a deficit which develops during the major period of neurogenesis between embryonic stages
John W Rumsey et al.
In vitro cellular & developmental biology. Animal, 49(8), 608-618 (2013-08-21)
One of the most important developmental modifications of the nervous system is Schwann cell myelination of axons. Schwann cells ensheath axons to create myelin segments to provide protection to the axon as well as increase the conduction of action potentials.
Davide D'Amico et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 42(2), 462-472 (2016-08-19)
The inability to properly extinguish fear memories constitutes the foundation of several anxiety disorders, including panic disorder. Recent findings show that boosting prefrontal cortex synaptic plasticity potentiates fear extinction, suggesting that therapies that augment synaptic plasticity could prove useful in

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