Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

860102P

Avanti

16:0 Phosphatidylpropanol

1,2-dipalmitoyl-sn-glycero-3-phosphopropanol (sodium salt), powder

Synonym(s):

1,2-dihexadecanoyl-sn-glycero-3-phosphopropanol (sodium salt)

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C38H74O8PNa
CAS Number:
92609-91-1
Molecular Weight:
712.95
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (860102P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860102P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCC)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C38H75O8P.Na/c1-4-7-9-11-13-15-17-19-21-23-25-27-29-31-37(39)43-34-36(35-45-47(41,42)44-33-6-3)46-38(40)32-30-28-26-24-22-20-18-16-14-12-10-8-5-2;/h36H,4-35H2,1-3H3,(H,41,42);/q;+1/p-1/t36-;/m1./s1

InChI key

SKVWIBXHTOHOAB-SKRAEFHRSA-M

General description

Phosphatidylpropanol is a low polarity phospholipid, which can be produced by the phospholipase D (PLD) specific transphosphatidylation reaction of phosphatidylcholine (PC) and propanol.

Application

16:0 Phosphatidylpropanol or 1,2-dipalmitoyl-sn-glycero-3-phosphopropanol is suitable for use as an internal standard in ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) to evaluate its matrix effect in blood samples for the validation of phosphatidylethanol (PEth). It may also be used as an internal standard for the quantification of PEth using liquid chromatography-mass spectrometry (LC-MS) in human blood.

Biochem/physiol Actions

Phosphatidylpropanol acts as a useful biomarker in phospholipase D activity assays.

Packaging

5 mL Amber Glass Screw Cap Vial (860102P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Natalie Kummer et al.
Analytical and bioanalytical chemistry, 408(3), 825-838 (2015-11-26)
Phosphatidylethanol species (PEths) are promising biomarkers of alcohol consumption. Here, we report on the set-up, validation, and application of a novel UHPLC-ESI-MS/MS method for the quantification of PEth 16:0/18:1, PEth 18:1/18:1, and PEth 16:0/16:0 in whole blood (30 μL) and
Mikhail Vyssotski et al.
Lipids, 44(4), 381-389 (2008-12-17)
High-performance TLC and (31)P-NMR were assessed as methods of observing the presence of numerous low polarity phospholipids: bis-phosphatidic acid (BPA), semi-lyso bis-phosphatidic acid (SLBPA), N-acyl phosphatidylethanolamine (NAPE), N-(1,1-dimethyl-3-oxo-butyl)-phosphatidylethanolamine (diacetone adduct of PE, DOBPE), N-acetyl PE, phosphatidylmethanol (PM), phosphatidylethanol (PEt), phosphatidyl-n-propanol
Siming Wang et al.
Talanta, 166, 315-320 (2017-02-19)
Phosphatidylethanol (PEth) is a special phospholipid that is only formed in the presence of ethanol, and therefore, serves as a promising biomarker for alcohol intake. In this study, a simple, rapid and precise method based on LC-MS/MS combined with ultrasound-assisted

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service