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840055C

Avanti

Liver PC

Avanti Research™ - A Croda Brand

Synonym(s):

L-α-phosphatidylcholine (Liver, Bovine)

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About This Item

CAS Number:
475662-36-3
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840055C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

10 mg/mL (840055C-25mg)

lipid type

phospholipids
phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylcholine (PC) is a strong bilayer-forming lipid found in mammalian membranes. It consists of a positively charged quaternary amine in the headgroup and a negatively charged phosphate group.

Application

Liver PC is suitable for use:
  • in the preparation of two dimensional crystals of microsomal glutathione transferase 1 for electron microscopy
  • in the preparation of ′golgi lipid′ mixture for liposome recruitment assay
  • in lipid vesicle preparation for ligand transfer assay

Biochem/physiol Actions

Phosphatidylcholine (PC) is an important source of diacylglycerol and other signaling molecules. Liver PC has a saturated to unsaturated fatty acid ratio of 0.91.

Packaging

5 mL Clear Glass Sealed Ampule (840055C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Stress sensor triggers conformational response of the integral membrane protein microsomal glutathione transferase 1
Busenlehner LS, et al.
Biochemistry, 43(35), 11145-11152 (2004)
GORAB scaffolds COPI at the trans-Golgi for efficient enzyme recycling and correct protein glycosylation
Witkos TM, et al.
Nature Communications, 10(1), 127-127 (2019)
The Membranes of Cells (2016)
Effect of bilayer phospholipid composition and curvature on ligand transfer by the alpha-tocopherol transfer protein
Zhang WX, et al.
Lipids, 44(7), 631-631 (2009)
The contribution of surface residues to membrane binding and ligand transfer by the alpha-tocopherol transfer protein (alpha-TTP)
Zhang WX, et al.
Journal of molecular biology, 405(4), 972-988 (2011)
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