765589
Gold nanoparticles
50 nm diameter, carboxylic acid functionalized, PEG 5000 coated, dispersion in H2O
Synonym(s):
Gold nanoparticles COOH functionalized, Au NP COOH, Gold Colloid
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About This Item
UNSPSC Code:
12162002
NACRES:
NA.23
Recommended Products
material
PEG 5000
Quality Level
form
dispersion in H2O
nanoparticles
packaging
poly bottle of 1 mL
OD
50
diameter
50 nm
pH
6.0-8.0 (25 °C)
solubility
water: miscible
density
1.00 g/cm3
λmax
535 nm
functional group
carboxylic acid
storage temp.
2-8°C
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General description
Carboxylic acid functionalized GNPs forms conjugates with various protein molecules due to the electrostatic attraction between negatively charged carboxylate groups and positively charged amino groups of protein.
Application
Gold nanoparticles 50 nm diameter, carboxylic acid functionalized, PEG 5000 coated, dispersion in H2O can be potentially used in the development of biosensors, cancer-cell imaging, drug delivery, and photothermal therapy.
AuNPs may also be used in the immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
AuNPs may also be used in the immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
The carboxylic acid group binds with proteins and is used in targeted drug delivery and gene therapy.
Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Functionalized gold nanoparticles and their biomedical applications
Nanomaterials, 1(1), 31-63 (2011)
Optical Fiber Sensors for Rapid Screening of COVID-19
Nag P, et al.
Transactions of the Indian National Academy of Engineering, 6, 1-4 (2020)
Size-dependent in vivo toxicity of PEG-coated gold nanoparticles
Zhang X, et al.
International journal of nanomedicine, 6, 2071-2071 (2011)
Nishima Wangoo et al.
Journal of colloid and interface science, 323(2), 247-254 (2008-05-20)
We report a novel strategy for the synthesis of aqueous stable, carboxylated gold nanoparticles (GNPs) by using glutamic acid as the reducing agent. The ratio of chloroaurate ions, AuCl(-)(4) to glutamic acid was optimized in the reaction medium to obtain
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