436240

BRIJ^® O20

average M_n ~1,150

• Synonym(s): Polyoxyethylene (20) oleyl ether
• Linear Formula: C₁₈H₃₅(OCH₂CH₂)_nOH, n~20
• CAS Number: 9004-98-2
• Molecular Weight: 1149.53
• MDL number: MFCD00074369
• UNSPSC Code: 12162002
• NACRES: NA.23

Properties

• description: non-ionic
• Quality Level: 200
• mol wt: average M_n ~1,150
• technique(s): cell culture | mammalian: suitable; protein quantification: suitable
• mp: 25-30 °C (lit.)
• HLB: 15
• SMILES string: O(CCO)CCCCCCCC\C=C/CCCCCCCC
• InChI: 1S/C20H40O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h9-10,21H,2-8,11-20H2,1H3/b10-9-
• InChI key: KWVPFECTOKLOBL-KTKRTIGZSA-N

Description

General description

Brij^® O20 is a non-ionic surfactant that has an 18 carbon tail with a single double bond and the head contains 20 ethylene oxide moieties. It is polyethoxylated fatty alcohol that is hydrophilic in nature.

Application

Brij^® O20 has been used:

• as a detergent in medium A to prepare single detergent micelle aggregates
• along with phosphate buffer saline (PBS) solution as the receptor solution for terbinafine (TBF) for in vitro permeation studies of TBF-free base in porcine skin
• as a detergent to isolate detergent-resistant membranes from the mouse brain and to determine the distribution of major mammalian brain gangliosides, GM1, GD1a, GD1b and GT1b

Legal Information

Brij is a registered trademark of Croda International PLC

Safety Information

• Pictograms: GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H315,H411
• Precautionary Statements: P264 - P273 - P280 - P302 + P352 - P332 + P313 - P362 + P364
• Hazard Classifications: Aquatic Chronic 2 - Skin Irrit. 2
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): >464.0 °F - Equilibrium method
• Flash Point(C): > 240 °C - Equilibrium method
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves