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Key Documents

192171

Sigma-Aldrich

DL-Alaninol

98%

Synonym(s):

(±)-2-Amino-1-propanol

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About This Item

Linear Formula:
CH3CH(NH2)CH2OH
CAS Number:
Molecular Weight:
75.11
Beilstein:
1209234
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

form

liquid

optical activity

[α]/D +1.0 to −1.0°

refractive index

n20/D 1.450 (lit.)

bp

173-176 °C (lit.)

density

0.943 g/mL at 25 °C (lit.)

functional group

amine
hydroxyl

SMILES string

CC(N)CO

InChI

1S/C3H9NO/c1-3(4)2-5/h3,5H,2,4H2,1H3

InChI key

BKMMTJMQCTUHRP-UHFFFAOYSA-N

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Application

DL-Alaninol has been used in the synthesis of:
  • N6-α-(I-hydroxypropyl) lysine
  • diastereomers of DL-β-amino alcohols
  • enantiopure and racemic samples of 2-methyl-N-tosylaziridine
  • (±)-3-(5-dimethylcarbamoyl-pent-1-enyl)-N-(2-hydroxy-1-methyl-ethyl)benzamide

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

183.2 °F - closed cup

Flash Point(C)

84 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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The role of lysine residues in the activity of 2-keto-3-deoxy-6-phosphogluconate aldolase.
J M Ingram et al.
The Journal of biological chemistry, 240(11), 4146-4151 (1965-11-01)
Ian C Stewart et al.
Journal of the American Chemical Society, 127(50), 17616-17617 (2005-12-15)
Sulfonylaziridines have been identified as excellent monomers for living ring-opening polymerization initiated by nucleophilic sulfonylamides. The resulting polymers exhibit low polydispersities and controllable molecular weights. The enantiopurity of the monomer plays a key role: racemic samples yield soluble polymers of
P M Hoi et al.
British journal of pharmacology, 152(5), 751-764 (2007-09-25)
A putative novel cannabinoid receptor mediates vasorelaxation to anandamide and abnormal-cannabidiol and is blocked by O-1918 and by high concentrations of rimonabant. This study investigates VSN16, a novel water-soluble agonist, as a vasorelaxant potentially acting at non-CB1, non-CB2 cannabinoid receptors
F Mergen et al.
Chemistry and physics of lipids, 59(3), 267-272 (1991-10-01)
N,N'-diacyl-1,3-diaminopropan-2-ols as amide isosteres of 1,3-diacylglycerols are obtained in 50-79% yields by treatment of 1,3-diaminopropan-2-ol with acid chlorides either in ether or THF in the presence of triethylamine and catalytic amounts of 4-dimethyl-aminopyridine. Subsequent acylation of the secondary alcohol function
Susana I de Azevedo Wäsch et al.
Applied and environmental microbiology, 68(5), 2368-2375 (2002-04-27)
Pseudomonas sp. strain KIE171 was able to grow with isopropylamine or L-alaninol [S-(+)-2-amino-1-propanol] as the sole carbon source, but not with D-alaninol. To investigate the hypothesis that L-alaninol is an intermediate in the degradation of isopropylamine, two mini-Tn5 mutants unable

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