185884

N,N-Dimethylacetamide

ReagentPlus^®, ≥99%

• Synonym(s): DMAc
• Linear Formula: CH₃CON(CH₃)₂
• CAS Number: 127-19-5
• Molecular Weight: 87.12
• Beilstein: 1737614
• EC Number: 204-826-4
• MDL number: MFCD00008686
• UNSPSC Code: 12352111
• eCl@ss: 39031204
• PubChem Substance ID: 329751718
• NACRES: NA.21

Properties

• vapor density: 3 (vs air)
• Quality Level: 100
• vapor pressure: 2 mmHg ( 25 °C); 4 mmHg ( 38 °C)
• product line: ReagentPlus^®
• Assay: ≥99%
• form: liquid
• autoignition temp.: 914 °F
• expl. lim.: 1.8 %, 100 °F; 11.5 %, 160 °F
• refractive index: n20/D 1.437 (lit.)
• pH: 4 (20 °C, 200 g/L)
• bp: 164.5-166 °C (lit.)
• mp: −20 °C (lit.)
• density: 0.937 g/mL at 25 °C (lit.)
• SMILES string: CN(C)C(C)=O
• InChI: 1S/C4H9NO/c1-4(6)5(2)3/h1-3H3
• InChI key: FXHOOIRPVKKKFG-UHFFFAOYSA-N

Description

General description

N,N-Dimethylacetamide (DMAc) is widely used to compose the solvent mixtures for cellulose. Static and dynamic light scattering studies of the cellulose dissolved in varying concentrations of DMAc/LiCl mixtures have been reported.

Application

N,N-Dimethylacetamide (DMAc) has been employed as an organic solvent for the liquid-phase exfoliation of pristine graphene from bulk graphite.
It may be used to compose the solvent system along with lithium chloride (LiCl) for the dissolution of commercial rayon grade cellulose. DMAc/LiCl solvent mixtures have been used for the preparation of chitin, cellulose and polyimide fibers and films.

N,N-Dimethylacetamide may be used in the preparation of α-lithio N,N-dimethylacetamide. DMAc along with palladium chloride forms an efficient catalytic system for the oxidation of several internal olefins to carbonyl compounds without undergoing isomerization.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H312 + H332,H319,H360D
• Precautionary Statements: P202 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point(F): 147.2 °F - closed cup
• Flash Point(C): 64 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves