Skip to Content
Merck
All Photos(1)

Documents

1012065

USP

Acyclovir

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Acycloguanosine, 9-[(2-Hydroxyethoxy)methyl]guanine, Acyclovir

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C8H11N5O3
CAS Number:
59277-89-3
Molecular Weight:
225.20
MDL number:
MFCD00057880
UNSPSC Code:
41116107
PubChem Substance ID:
329748935
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

acyclovir

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

NC1=Nc2c(ncn2COCCO)C(=O)N1

InChI

1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)

InChI key

MKUXAQIIEYXACX-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Acyclovir is a nucleoside analogue antiviral drug. It is a highly potent inhibitor of herpes simplex virus. It is related to cytarabine, idoxuridine, trifluridine and vidarabine.

Application

Acyclovir USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Acyclovir Capsules
  • Acyclovir for Injection
  • Acyclovir Injection
  • Acyclovir Ointment
  • Acyclovir Oral Suspension
  • Acyclovir Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

A0220000

Aciclovir, European Pharmacopoeia (EP) Reference Standard

1012076

Acyclovir Related Compound A, United States Pharmacopeia (USP) Reference Standard

Y0001264

Aciclovir for system suitability, European Pharmacopoeia (EP) Reference Standard

Y0001271

Aciclovir for peak identification 1, European Pharmacopoeia (EP) Reference Standard

1012087

Acyclovir Related Compound G, United States Pharmacopeia (USP) Reference Standard

1012054

Acyclovir Related Compound F, United States Pharmacopeia (USP) Reference Standard

BP438

Aciclovir, British Pharmacopoeia (BP) Reference Standard

Y0002245

Aciclovir for system suitability A, CRS, European Pharmacopoeia (EP) Reference Standard

Y0002244

Aciclovir for impurity G identification, European Pharmacopoeia (EP) Reference Standard

Y0002242

Aciclovir for impurity C identification, CRS, European Pharmacopoeia (EP) Reference Standard

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Derivative spectrophotometric method for determination of acyclovir in polymeric nanoparticles.
Tavares, Guilherme Diniz, et al.
Quimica nova, 35.1, 203-206 (2012)
D M Richards et al.
Drugs, 26(5), 378-438 (1983-11-01)
Acyclovir (aciclovir) is a nucleoside analogue antiviral drug related to cytarabine, idoxuridine, trifluridine and vidarabine. In common with these earlier antivirals, acyclovir is active against some members of the herpesvirus group of DNA viruses. The efficacy of topical acyclovir has
G B Elion
The American journal of medicine, 73(1A), 7-13 (1982-07-20)
Acyclovir, an acrylic purine nucleoside analog, is a highly potent inhibitor of herpes simplex virus (HSV), types 1 and 2, and varicella zoster virus, and has extremely low toxicity for the normal host cells. This selectivity is due to the
Ahlem Ben Sassi et al.
The Indian journal of medical research, 127(2), 183-192 (2008-04-12)
Tunisian Chrysanthemum species are known to have medicinal activity and some of the species are used in traditional medicine. We have earlier shown the use of C. trifurcatum flowerheads in Tunisian traditional medicine to treat constipation. In the present study
S Leflore et al.
Drug safety, 23(2), 131-142 (2000-08-17)
The objective of this article is to review and evaluate risks and benefits associated with the use of acyclovir in the treatment and prophylaxis of common manifestations of herpes simplex virus (HSV) infections in immunocompetent and immunocompromised patients. Information was
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service