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Supelco

Discovery® Cyano (5 µm) HPLC Columns

L × I.D. 2 cm × 4 mm Supelguard Guard Cartridge, pkg of 2 ea, Guard Cartridge holder required for use

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About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

Product Name

Discovery® Cyano Supelguard Cartridge, 5 μm particle size, L × I.D. 2 cm × 4 mm

material

stainless steel column

Agency

suitable for USP L10

description

Supelguard Cartridge

product line

Discovery®

feature

endcapped

packaging

pkg of 2 ea

technique(s)

HPLC: suitable

L × I.D.

2 cm × 4 mm

surface area

200 m2/g

matrix

fully porous particle

matrix active group

cyano phase

particle size

5 μm

pore size

180 Å

operating pH

2-8

application(s)

food and beverages

separation technique

hydrophilic interaction (HILIC)
normal phase
reversed phase

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Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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Graciela B Arhancet et al.
Journal of medicinal chemistry, 53(16), 5970-5978 (2010-08-03)
A new 1,4-dihydropyridine 5a, containing a cyano group at the C3 position, was recently reported to possess excellent mineralocorticoid receptor (MR) antagonist in vitro potency and no calcium channel-blocker (CCB) activity. In the present study, we report the structure-activity relationships
K Umekawa et al.
Japanese journal of pharmacology, 84(1), 7-15 (2000-10-24)
We describe the pharmacological characteristics of SM-19712 (4-chloro-N-[[(4-cyano-3-methyl-1-phenyl-1H-pyrazol-5-yl)amino]carbonyl] benzenesulfonamide, monosodium salt). SM-19712 inhibited endothelin converting enzyme (ECE) solubilized from rat lung microsomes with an IC50 value of 42 nM and, at 10 - 100 microM, had no effect on other
T A Verdoorn et al.
European journal of pharmacology, 269(1), 43-49 (1994-09-15)
The diversity of neuronal glutamate receptors continues to increase with the discovery of multiple subunits and subunit families. The significance of this potential receptor heterogeneity is unknown because pharmacological tools that could clearly distinguish between different structural isoforms have not
Ye Ding et al.
Chemical communications (Cambridge, England), 47(33), 9495-9497 (2011-07-19)
A novel and facile DDQ-mediated dehydrogenation from natural rigid polycyclic acids or flexible alkyl acids to generate lactones is described. The formation of lactones proceeds by a radical ion mechanism, which has been established by DPPH˙-mediated chemical identification, ESR spectroscopy
Patrick Igel et al.
Journal of medicinal chemistry, 52(20), 6297-6313 (2009-10-02)
Recently, we identified high-affinity human histamine H3 (hH3R) and H4 receptor (hH4R) ligands among a series of NG-acylated imidazolylpropylguanidines, which were originally designed as histamine H2 receptor (H2R) agonists. Aiming at selectivity for hH4R, the acylguanidine group was replaced with
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