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P2533

Sigma-Aldrich

Poly-L-ornithine hydrochloride

suitable for ligand binding assays, Mol wt 15,000-30,000

Synonym(s):

L-Ornithine homopolymer hydrochloride

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About This Item

CAS Number:
26982-21-8
MDL number:
MFCD00166412
UNSPSC Code:
12352209
PubChem Substance ID:
24898334
NACRES:
NA.26

product name

Poly-L-ornithine hydrochloride, mol wt 15,000-30,000

form

powder or solid

Quality Level

200

mol wt

15,000-30,000

technique(s)

ligand binding assay: suitable

color

white to off-white

storage temp.

−20°C

SMILES string

Cl.NCCCC(N)C(O)=O

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Application

Poly-L-ornithine hydrochloride has been used as a substrate analog of acetyl-poly-L-lysine to study substrate binding and catalysis of the NAD-dependent protein deacetylase Hst2. It has been used to bind alginate-polycation-alginate (APA) microcapsules.

Biochem/physiol Actions

Poly-L-ornithine is a polycationic synthetic amino acid polymer. It boosts nasal absorption of hydrophilic macromolecular drugs. Poly-L-ornithine is a specialized coating that acts as a charge modifier.

Analysis Note

Molecular weight based on viscosity.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications

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