P0184
Pseudomonas exotoxin A from Pseudomonas aeruginosa
lyophilized powder
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About This Item
General description
Pseudomonas exotoxin A is secreted by Pseudomonas aeruginosa. It is a member of the family mono-ADP-ribosyltransferases.
Biochem/physiol Actions
Pseudomonas exotoxin A functions as an anticancer agent.
It catalyses the transfer of ADP-ribose moiety of NAD+ to the histidine imidazole ring of diphthamide.
Shown to be toxic to animals and to cell lines, and to inhibit protein synthesis via ADP ribosylation of elongation factor 2.
It catalyses the transfer of ADP-ribose moiety of NAD+ to the histidine imidazole ring of diphthamide.
Shown to be toxic to animals and to cell lines, and to inhibit protein synthesis via ADP ribosylation of elongation factor 2.
Packaging
Package size based on protein content.
Physical form
Lyophilized powder containing Tris buffer, EDTA, NaCl and lactose
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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